What is the most famous road in the United States?

The most famous road in the United States is Route 66, also known as the “Main Street of America.” Stretching from Chicago, Illinois, to Santa Monica, California, Route 66 was one of the original highways in the U.S. Highway System, running through eight states and covering nearly 2,500 miles. It became a symbol of American freedom and exploration during the Great Depression and the rise of the automobile culture. Today, Route 66 is celebrated in popular culture, with roadside attractions, museums, and historic motels marking its path, making it a popular route for road trips.